For doctors

A balance of safety and efficacy

Ultracol is the first PDO microsphere collagen biostimulator. Predictable, degrading within 6–8 months, with controlled particle size.

Ordering and training
Ultracol 100 и 200

Why PDO microspheres

01

Predictable degradation

PDO hydrolyses within 6–8 months. A short active period means less overlap between repeat sessions.

02

Controlled size

10–50 µm (100) and 30–110 µm (200), within the range for a controlled response without phagocytosis of the particles.

03

Smooth, non-porous spheres

Uniform shape and a smooth surface for even distribution and predictable stimulation.

04

Balanced properties

PDO is more hydrophilic than PLLA and PCL, and soft and flexible at body temperature.

See the research

Specifications

—Ultracol 100Ultracol 200
Composition75 mg PDO + 25 mg Na-CMC150 mg PDO + 50 mg Na-CMC
Particle size10–50 µm30–110 µm
FormFreeze-dried powderFreeze-dried powder
LayerMid to deep dermisUpper subcutaneous layer
DeviceNeedle 27–31GCannula 21–23G
Effect6–12 months6–12 months
StorageBelow 30 °C, do not freezeBelow 30 °C, do not freeze

MFDS No. 20-598 (Korea, 2020, Class IV) · CE (MDD, 2021) · Registered in 30 countries, including Bulgaria. Manufacturer: Ultra V Co., Ltd. / LYV Sciences.

Protocol per the manufacturer’s guide

—Ultracol 100Ultracol 200
Reconstitution3 ml water for injection + 1 ml lidocaine with epinephrine (4 ml total)Same
TechniqueSerial puncture, manual or multi-injectorCannula, fanning, retrograde; 45° entry into the subcutis
Volume1 vial for the full face1–2 vials for the full face; 1 vial for one area
AnaesthesiaNumbing creamNumbing cream + local lidocaine
Course3 sessions 1 month apart, then 3 at 3-month intervals2 sessions 2 months apart, 1 after 3–6 months, maintenance every 6–12 months
CombinationsMix 1:1 with non- or lightly crosslinked HA, polynucleotides, exosomesRF cannula, thread lifting, botulinum toxin
AftercareCryotherapy or LDM for swelling; antibiotic and NSAID for 2–3 days at your discretionSame

Always follow the product’s instructions for use (IFU).

Information for healthcare professionals

The following information is intended only for doctors and healthcare professionals.

Ordering and training

Work with genuine Ultracol

Remedy Technology is the exclusive distributor of Ultracol in Bulgaria. We provide the genuine product, training in injection techniques, and a listing for your clinic on the site’s clinic map.

  • Genuine, traceable product
  • Hands-on training
  • A place in "Find a clinic"
  • Patient materials

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